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WDFY1 Antibody, FITC conjugated

Datasheet
Code CSB-PA816890LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WDFY1 Polyclonal antibody
Uniprot No.
Q8IWB7
Target Names
WDFY1
Alternative Names
FENS 1 antibody; FENS-1 antibody; FENS1 antibody; KIAA1435 antibody; Phosphoinositide binding protein 1 antibody; Phosphoinositide binding protein SR1 antibody; Phosphoinositide-binding protein 1 antibody; WD repeat and FYVE domain containing 1 antibody; WD repeat and FYVE domain-containing protein 1 antibody; WD40 and FYVE domain containing protein 1 antibody; WD40- and FYVE domain-containing protein 1 antibody; WDF1 antibody; WDFY1 antibody; WDFY1_HUMAN antibody; ZFYVE17 antibody; Zinc finger FYVE domain containing protein 17 antibody; Zinc finger FYVE domain-containing protein 17 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human WD repeat and FYVE domain-containing protein 1 protein (261-357AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

WDFY1 Antibodies

WDFY1 Proteins

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Target Background

Function
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.
Gene References into Functions
  1. NRP2 inhibits WDFY1 transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1). PMID: 27026195
  2. WDFY1 mediates TLR3/TLR4 signaling by recruiting TRIF. PMID: 25736436
Subcellular Location
Early endosome.
Database Links

HGNC: 20451

KEGG: hsa:57590

STRING: 9606.ENSP00000233055

UniGene: Hs.368359

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